Stromatoxin 1

Stromatoxin 1, a peptide isolated from tarantulas, acts as an inhibitor of various potassium channels, including K (V) 2.1, K (V) 2.2, K (V) 4.2, and K (V) 2.1/9.3. It selectively targets K (V) 2.1 and K (V) 2.2 channel subunits, which are crucial in counteracting myogenic and neurogenic contractions of rat urinary bladder smooth muscle (UBSM) [1].