αC-Conotoxin PrXA
Product Specifications
Target
AChR
Related Pathways
Neuroscience
Bioactivity
αC-Conotoxin PrXA is a neurotoxic paralytic peptide acting as a competitive antagonist of the nicotinic acetylcholine receptor (nAChR), exhibiting inhibitory constants (IC50) of 1.8 nM for the adult α1β1εδ subtype and 3.0 nM for the fetal α1β1γδ subtype. The compound vies with α-bungarotoxin for binding sites at the α/δ and α/γ interfaces of neuromuscular nAChRs, demonstrating high selectivity[1].
Molecular Formula
C160H247N43O44S2
Molecular Weight
3541.06
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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