αC-Conotoxin PrXA
Product Specifications
Target
AChR
Related Pathways
Neuroscience
Bioactivity
?C-Conotoxin PrXA is a neurotoxic paralytic peptide acting as a competitive antagonist of the nicotinic acetylcholine receptor (nAChR), exhibiting inhibitory constants (IC50) of 1.8 nM for the adult ?1?1?? subtype and 3.0 nM for the fetal ?1?1?? subtype. The compound vies with ?-bungarotoxin for binding sites at the ?/? and ?/? interfaces of neuromuscular nAChRs, demonstrating high selectivity[1].
Molecular Formula
C160H247N43O44S2
Molecular Weight
3541.06
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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