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μ-Conotoxin PIIIA

Product Specifications

CAS Number

184840-20-8

Target

Sodium Channel

Related Pathways

Membrane transporter/Ion channel

Bioactivity

?-Conotoxin PIIIA, isolated from Conus purpurascens [1] [2], is a blocker of the sodium channel NaV 1.4.

Smiles

O=C1N2[C@@](C[C@@H](O)C2)(C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@]3(C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@]4(CSSC[C@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]5NC(=O)CC5)CCCNC(=N)N)=O)CC(C)C)=O)C(=O)N[C@](C(=O)NCC(=O)N[C@H]1CC6=CC=CC=C6)(CSSC[C@](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC7=CN=CN7)NC(=O)[C@]8(N(C(=O)[C@H](CCCCN)NC4=O)C[C@H](O)C8)[H])(C(=O)N[C@H](C(N)=O)CSSC3)[H])[H])[H])[H])[H]