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Z-Pro-Pro-aldehyde-dimethyl acetal

Product Specifications

CAS Number

170116-63-9

Target

Prolyl Endopeptidase (PREP)

Related Pathways

Metabolism|||Proteases/Proteasome

Bioactivity

Z-Pro-Pro-aldehyde-dimethyl acetal is a potent prolyl endopeptidase (PREP) inhibitor, effectively impeding the activity of this cytoplasmic serine endoprotease with an IC50 of 12 nM. Its significance lies in its role in modulating cognitive dysfunction associated with aging and neurodegenerative conditions, such as Alzheimer's disease [1] [2].

Smiles

C(=O)(N1[C@H](C(OC)OC)CCC1)[C@H]2N(C(OCC3=CC=CC=C3)=O)CCC2

Molecular Formula

C20H28N2O5

Molecular Weight

376.45

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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