Z-Pro-Pro-aldehyde-dimethyl acetal
Product Specifications
CAS Number
170116-63-9
Target
Prolyl Endopeptidase (PREP)
Related Pathways
Metabolism|||Proteases/Proteasome
Bioactivity
Z-Pro-Pro-aldehyde-dimethyl acetal is a potent prolyl endopeptidase (PREP) inhibitor, effectively impeding the activity of this cytoplasmic serine endoprotease with an IC50 of 12 nM. Its significance lies in its role in modulating cognitive dysfunction associated with aging and neurodegenerative conditions, such as Alzheimer's disease [1] [2].
Smiles
C(=O)(N1[C@H](C(OC)OC)CCC1)[C@H]2N(C(OCC3=CC=CC=C3)=O)CCC2
Molecular Formula
C20H28N2O5
Molecular Weight
376.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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