Μ-Conotoxin-CnIIIC

?-Conotoxin-CnIIIC, a 22-residue conopeptide derived from Conus consors, acts as a potent and persistent NaV1.4 channel blocker, exhibiting analgesic, anaesthetic, and myorelaxant properties [1] [2].

C(C=1C=2C(NC1)=CC=CC2)[C@H]3C(=O)N[C@@]4(C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC5=CN=CN5)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@]6(CSSC[C@](NC(=O)[C@@H](NC(CNC(=O)[C@@H]7CCC(=O)N7)=O)CSSC4)(C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N8[C@](C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@](C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N3)(CSSC[C@@H](C(N)=O)NC6=O)[H])(CCC8)[H])[H])[H])[H]