Taxamairin B
Product Specifications
CAS Number
110300-77-1
Target
TNF, Others, Reactive Oxygen Species, PI3K, Interleukin
Related Pathways
PI3K/Akt/mTOR signaling, Apoptosis, Metabolism, NF-κB, Others, Immunology/Inflammation
Bioactivity
Taxamairin B is a potent anti-inflammatory compound that inhibits the expression of proinflammatory cytokines (TNF-α, IL-1β, and IL-6) and reduces the production of NO and ROS in LPS-induced RAW264.7 cells. Additionally, it shows substantial protective effects against LPS-induced acute lung injury in mice [1] [2].
Smiles
O(C)C1=C2C(=CC(C(C)C)=C1OC)C(=O)C=C3C(=C2)C=CC(=O)C3(C)C
Molecular Formula
C22H24O4
Molecular Weight
352.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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