Feralolide
Product Specifications
CAS Number
149418-38-2
Target
Others, Cholinesterase (ChE)
Related Pathways
Neuroscience, Others
Bioactivity
Feralolide, a dihydroisocoumarin from the methanolic extract of aloe vera resin, functions as a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), with IC50 values of 55 μg/mL and 52 μg/mL, respectively. It exhibits antioxidant properties, effectively inhibiting 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) . Research suggests feralolide's potential in studying cognitive disorders, including Alzheimer's disease, for its memory restoration and enhancement capabilities [1].
Smiles
O=C1C=2C(C[C@@H](CC3=C(C(C)=O)C(O)=CC(O)=C3)O1)=CC(O)=CC2O
Molecular Formula
C18H16O7
Molecular Weight
344.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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