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GRK2 Inhibitor 2

Product Specifications

CAS Number

2592436-21-8

Target

Aurora Kinase, Others, GRK

Related Pathways

Cell Cycle/Checkpoint, GPCR/G Protein, Others, Chromatin/Epigenetic

Bioactivity

GRK2 Inhibitor 2 (Compound 8h), with an IC50 of 19 nM for GRK2 and 137 nM for Aurora-A, enhances β-AR-mediated cAMP accumulation in GRK2-overexpressing HEK293 cells. It is utilized in congestive heart failure (HF) research [1].

Smiles

O=C1C=2C(=CC=C(C2)C=3C=NNC3)C=NN1CC4=CC(OC)=CC=C4

Molecular Formula

C19H16N4O2

Molecular Weight

332.36

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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