ON 108600
Product Specifications
CAS Number
1585246-23-6
Target
Casein Kinase, DYRK
Related Pathways
Stem Cells, Metabolism, Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint
Bioactivity
ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 μM and 0.007 μM for DYRK1A and DYRK1B, 0.028 μM for DYRK2, 0.05 μM and 0.005 μM for CK2α1 and CK2α2, and 0.005 μM for TNIK, respectively. This compound exhibits antitumor activity [1].
Smiles
O=[N+](C(C=C1/C=C2SC3=CC=C(C=C3NC\2=O)S(CC4=C(C=CC=C4Cl)Cl)(=O)=O)=C(C=C1)O)[O-]
Molecular Formula
C22H14Cl2N2O6S2
Molecular Weight
537.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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