ON 108600
Product Specifications
CAS Number
1585246-23-6
Target
Casein Kinase|||DYRK
Related Pathways
Stem Cells|||Metabolism|||Tyrosine Kinase/Adaptors|||Cell Cycle/Checkpoint
Bioactivity
ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 ?M and 0.007 ?M for DYRK1A and DYRK1B, 0.028 ?M for DYRK2, 0.05 ?M and 0.005 ?M for CK2?1 and CK2?2, and 0.005 ?M for TNIK, respectively. This compound exhibits antitumor activity [1].
Smiles
O=[N+](C(C=C1/C=C2SC3=CC=C(C=C3NC\2=O)S(CC4=C(C=CC=C4Cl)Cl)(=O)=O)=C(C=C1)O)[O-]
Molecular Formula
C22H14Cl2N2O6S2
Molecular Weight
537.39
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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