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ON 108600

Product Specifications

CAS Number

1585246-23-6

Target

Casein Kinase, DYRK

Related Pathways

Stem Cells, Metabolism, Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint

Bioactivity

ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 μM and 0.007 μM for DYRK1A and DYRK1B, 0.028 μM for DYRK2, 0.05 μM and 0.005 μM for CK2α1 and CK2α2, and 0.005 μM for TNIK, respectively. This compound exhibits antitumor activity [1].

Smiles

O=[N+](C(C=C1/C=C2SC3=CC=C(C=C3NC\2=O)S(CC4=C(C=CC=C4Cl)Cl)(=O)=O)=C(C=C1)O)[O-]

Molecular Formula

C22H14Cl2N2O6S2

Molecular Weight

537.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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