Cbl-b-IN-13

2368841-85-2

E1/E2/E3 Enzyme

Ubiquitination

Cbl-b-IN-13 (Example 520) is a potent Cbl-b inhibitor with an IC50 of less than 100 nM, capable of activating T-cells [1].

O=C1C2=CC(=CC(=C2CN1C3=CC=CC(=C3)C4(COC4)CC5=NN=CN5C)C(F)(F)F)CN6CCC7(C6)CC7

C29H30F3N5O2

537.58

Cool pack

-20°C