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Cbl-b-IN-8

Product Specifications

CAS Number

2815223-33-5

Target

E1/E2/E3 Enzyme

Related Pathways

Ubiquitination

Bioactivity

Cbl-b-IN-8 (Compound 293) is an inhibitor of casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, with half maximal inhibitory concentrations (IC50s) of 5.5 nM and 7.8 nM, respectively [1].

Smiles

C(C1(COC1)C=2C=C(N=C(OC3CCCC3)C2)N4CC=5C(C4=O)=CC(CN6[C@@H]([C@H](C)C)CN(C)CC6)=CC5C(F)(F)F)C=7N(C)C=NN7

Molecular Formula

C35H44F3N7O3

Molecular Weight

667.76

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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