Cbl-b-IN-7

Product Specifications

CAS Number

2815221-35-1

Target

E1/E2/E3 Enzyme

Related Pathways

Ubiquitination

Bioactivity

Cbl-b-IN-7 (Compound 248) is an inhibitor of casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, with half-maximal inhibitory concentrations (IC50s) of 6.7 nM and 5.2 nM, respectively [1].

Smiles

[C@@H](F)(C1(COC1)C2=CC(=CC=C2)N3CC=4C(C3=O)=CC([C@@H](NC5(C)CCC5)C)=CC4C(F)(F)F)C=6N(C)C=NN6

Molecular Formula

C29H31F4N5O2

Molecular Weight

557.58

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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