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Cbl-b-IN-6

Product Specifications

CAS Number

2815221-33-9

Target

E1/E2/E3 Enzyme

Related Pathways

Ubiquitination

Bioactivity

Cbl-b-IN-6 (Compound 246) is an inhibitor of casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, with half-maximal inhibitory concentrations (IC50s) of 6.7 nM for Cbl-b and 5.2 nM for c-Cbl, respectively [1].

Smiles

C(C1(CC(F)(F)C1)C2=CC(=CC=C2)N3CC=4C(C3=O)=CC([C@@H](NC5(C)CCC5)C)=CC4C(F)(F)F)C=6N(C)C=NN6

Molecular Formula

C30H32F5N5O

Molecular Weight

573.6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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