JAK-IN-31
Product Specifications
CAS Number
2597016-88-9
Target
JAK
Related Pathways
Chromatin/Epigenetic, Angiogenesis, Tyrosine Kinase/Adaptors, Stem Cells, JAK/STAT signaling
Bioactivity
JAK-IN-31 (Example 75), a JAK inhibitor, demonstrates IC50 values of ≤0.01 μM for JAK1, ≤0.01 μM for JAK2, 0.01-0.1 μM for JAK3, and ≤0.01 μM for Tyk2, indicating potent activity across these targets. It is utilized in cancer research [1].
Smiles
N(C=1C(=CN=C2C1C=CN2)C=3SC(C)=NN3)[C@@H]4C[C@H](NS(=O)(=O)C5=CC(C#N)=CC=C5)C4
Molecular Formula
C21H19N7O2S2
Molecular Weight
465.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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