Hydroxy-PP-Me
Product Specifications
CAS Number
833481-77-9
Target
Apoptosis|||NADPH|||ROS
Related Pathways
Immunology/Inflammation|||Metabolism|||Apoptosis
Purity
0.9992
Bioactivity
Hydroxy-PP-Me is a potent and specific CBR1 inhibitor with an IC50 of 759 nM. It inhibits serum-withdrawal-induced apoptosis and, when used in conjunction with As2O3, enhances As2O3-induced apoptotic cell death [1] [2].
Smiles
OC1=CC=CC(=C1)C2=CN(C=3N=CN=C(NC)C32)C(C)C
Molecular Formula
C16H18N4O
Molecular Weight
282.34
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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