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TNG-462

Product Specifications

CAS Number

2760483-96-1

Target

Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic

Purity

0.987

Bioactivity

TNG-462 is a potent and selective PRMT5 inhibitor with antitumor activity and oral activity, primarily for the treatment of methylthioadenosine phosphorylase (MTAP) -deficient and/or methylthioadenosine (MTA) -accumulating cancers (e.g., non-small-cell lung cancer, pancreatic cancer, bladder cancer, and hematologic malignancies) .

Smiles

C(C(NC=1C=C(CC)C(N)=NC1)=O)(=O)N2[C@H](CC[C@H](C)C2)C=3C=C4C(=CC3)SC(=N4)C5CCN(C)CC5

Molecular Formula

C28H36N6O2S

Molecular Weight

520.69

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/123792264022458652/T79873

Available Sizes

Curated Selection

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