TNG-462
Product Specifications
CAS Number
2760483-96-1
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Purity
0.987
Bioactivity
TNG-462 is a potent and selective PRMT5 inhibitor with antitumor activity and oral activity, primarily for the treatment of methylthioadenosine phosphorylase (MTAP) -deficient and/or methylthioadenosine (MTA) -accumulating cancers (e.g., non-small-cell lung cancer, pancreatic cancer, bladder cancer, and hematologic malignancies) .
Smiles
C(C(NC=1C=C(CC)C(N)=NC1)=O)(=O)N2[C@H](CC[C@H](C)C2)C=3C=C4C(=CC3)SC(=N4)C5CCN(C)CC5
Molecular Formula
C28H36N6O2S
Molecular Weight
520.69
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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