TIE-2/VEGFR-2 kinase-IN-4
Product Specifications
CAS Number
433224-29-4
Target
VEGFR|||Others|||Tie-2
Related Pathways
Others|||Angiogenesis|||Tyrosine Kinase/Adaptors
Bioactivity
TIE-2/VEGFR-2 kinase-IN-4, a benzimidazole derivative, is a potent inhibitor of the tyrosine kinase receptors TIE-2 and VEGFR-2, with IC50 values of 5.2 nM and 5.1 nM, respectively. This compound is utilized in angiogenesis research [1].
Smiles
N(C(=O)C1=CC=CO1)C=2NC=3C(N2)=CC=C(OC4=CC=C(NC(NC5=CC(C(F)(F)F)=CC=C5F)=O)C=C4)C3
Molecular Formula
C26H17F4N5O4
Molecular Weight
539.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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