TIE-2/VEGFR-2 kinase-IN-3
Product Specifications
CAS Number
433224-09-0
Target
Others|||Tie-2|||VEGFR
Related Pathways
Tyrosine Kinase/Adaptors|||Others|||Angiogenesis
Bioactivity
TIE-2/VEGFR-2 kinase-IN-3, a benzimidazole derivative, is a potent inhibitor of tyrosine kinase receptors TIE-2 and VEGFR-2, with IC50 values of 6.9 nM and 3.5 nM, respectively. This compound is useful for angiogenesis research [1].
Smiles
N(C(OC)=O)C=1NC=2C(N1)=CC=C(SC3=CC=C(NC(NC4=CC(C(F)(F)F)=CC=C4F)=O)C=C3)C2
Molecular Formula
C23H17F4N5O3S
Molecular Weight
519.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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