PROTAC MLKL Degrader-1
Product Specifications
Target
MLK|||Others|||PROTACs
Related Pathways
MAPK|||PROTAC|||Others
Bioactivity
PROTAC MLKL Degrader-1 (Compound 36) is a selective PROTAC degrader targeting MLKL, with a degradation maximum (D max) exceeding 90%. The compound incorporates modified cereblon (CRBN) ligands and a lenalidomide-linker within its structure, effectively inhibiting cell death in a TSZ-induced model of necroptosis.
Molecular Formula
C46H55F2N9O9S
Molecular Weight
948.05
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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