DGKα-IN-3
Product Specifications
CAS Number
2648418-86-2
Target
Others
Related Pathways
Others
Bioactivity
DGKα-IN-3 (example 25), with an IC50 of 283 nM, is a selective DGKα inhibitor that enhances anti-PD-1's anti-tumor activity by promoting T cell proliferation and function, highlighting its potential for cancer and immunology research applications.
Smiles
C(N)(=O)C1=C(N2CCC3(CN(CC3)C4=CC=C(OC(F)(F)F)C=C4)CC2)C=5C(N(C)C1=O)=CC=CC5
Molecular Formula
C26H27F3N4O3
Molecular Weight
500.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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