KRAS G12C inhibitor 61
Product Specifications
CAS Number
2300967-40-0
Target
Kras, ERK, Ras
Related Pathways
MAPK, GPCR/G Protein
Bioactivity
KRAS G12C inhibitor 61 (Example 3) demonstrates potent activity by inhibiting phospho-ERK 1/2 in MIA PaCa-2 cells, with an IC50 value of 9 nM, and is applicable in the research of pancreatic, colorectal, and lung cancers [1].
Smiles
O=C1N(C=2C(C(=N1)N3C(C)CN(C(C=C)=O)C(C)C3)=CC(Cl)=C(N2)C4=C(F)C=CC=C4N)C5=C(C(C)C)N=CC=C5C
Molecular Formula
C31H33ClFN7O2
Molecular Weight
590.09
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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