JAK kinase-IN-1
Product Specifications
CAS Number
2698389-43-2
Target
JAK
Related Pathways
Chromatin/Epigenetic, Angiogenesis, JAK/STAT signaling, Stem Cells, Tyrosine Kinase/Adaptors
Bioactivity
JAK kinase-IN-1 (Example 1) is a potent inhibitor targeting the JAK family, including TYK2, JAK1, JAK2, and JAK3, with IC50 values of 4.2 nM, 32 nM, 27 nM, and 3473 nM, respectively [1].
Smiles
C(=O)(N1C2(CN(CC1(SC2)[H])C3=NC(NC=4C=NN(C)C4)=NC=C3)[H])[C@H]5C(F)(F)C5
Molecular Formula
C17H19F2N7OS
Molecular Weight
407.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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