PHD-IN-1
Product Specifications
CAS Number
2924182-31-8
Target
HIF/HIF Prolyl-Hydroxylase
Related Pathways
Metabolism, Chromatin/Epigenetic
Bioactivity
PHD-IN-1 (compound 80) is a potent PHD2 inhibitor with an IC50 value of ≤5 nM and demonstrates EC50 values of 2.5 μM in EPO Elisa assays in both Caco2-HIF1a-HiBiT-clone-1 and Hep3B cell lines [1].
Smiles
OC=1C2=C(N=C(N3[C@@]4(CN([C@](C3)(C4)[H])C5CC5)[H])C=C2)C=NC1C(NCC=6C=CC(C#N)=NC6)=O
Molecular Formula
C24H23N7O2
Molecular Weight
441.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LS002913-20ug 20 µg
Metabotropic Glutamate Receptor 3 (GRM3) (NM_000840) Human Over-expression Lysate
Sign In for Pricing
View Details 
MBS1247803-01 0.02 mg (E-Coli)
Recombinant Arabidopsis thaliana Transcription factor bHLH106 (BHLH106)
Sign In for Pricing
View Details MBS1247803-02 0.1 mg (E-Coli)
Recombinant Arabidopsis thaliana Transcription factor bHLH106 (BHLH106)
Sign In for Pricing
View Details MBS1247803-03 0.02 mg (Yeast)
Recombinant Arabidopsis thaliana Transcription factor bHLH106 (BHLH106)
Sign In for Pricing
View Details MBS1247803-04 0.1 mg (Yeast)
Recombinant Arabidopsis thaliana Transcription factor bHLH106 (BHLH106)
Sign In for Pricing
View Details