TNIK&MAP4K4-IN-1
Product Specifications
CAS Number
2478592-86-6
Target
Others, MAPK
Related Pathways
Others, MAPK
Bioactivity
TNIK&MAP4K4-IN-1 (compound A-39) is a potent dual inhibitor of TNIK and MAP4K4/HGK, with IC50 values of 1.29 nM and <10 nM, respectively, in human hepatic stellate cell LX-2, and is applicable in cancer and fibrosis inhibition [1].
Smiles
C(NC=1C(OC)=CN=CC1)(=O)C=2OC(C3=C(N=CN3C4CCCC4)C5=CC=C(F)C=C5)=CC2
Molecular Formula
C25H23FN4O3
Molecular Weight
446.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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