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TNIK&MAP4K4-IN-1

Product Specifications

CAS Number

2478592-86-6

Target

Others, MAPK

Related Pathways

Others, MAPK

Bioactivity

TNIK&MAP4K4-IN-1 (compound A-39) is a potent dual inhibitor of TNIK and MAP4K4/HGK, with IC50 values of 1.29 nM and <10 nM, respectively, in human hepatic stellate cell LX-2, and is applicable in cancer and fibrosis inhibition [1].

Smiles

C(NC=1C(OC)=CN=CC1)(=O)C=2OC(C3=C(N=CN3C4CCCC4)C5=CC=C(F)C=C5)=CC2

Molecular Formula

C25H23FN4O3

Molecular Weight

446.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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