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GPX4-IN-7

Product Specifications

Target

Ferroptosis

Related Pathways

Apoptosis

Bioactivity

GPX4-IN-7 (Compound 31), an indirubin derivative, serves as a ferroptosis inducer in colon cancer treatment. Exhibiting potent antitumor properties, it inhibits HCT-116 cell growth with an IC50 of 0.49 μM. This compound also facilitates GPX4 degradation, leading to lipid ROS accumulation, thereby inducing ferroptosis [1].

Molecular Formula

C25H23ClN4O4

Molecular Weight

478.93

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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