FB49
Product Specifications
Target
Autophagy, Apoptosis
Related Pathways
Apoptosis, Autophagy
Bioactivity
FB49 is a selective Bcl-2-associated athanogene 3 (BAG3) inhibitor with a Ki of 45 μM. It inhibits the proliferation of human tumoral cells without affecting the viability of human peripheral mononuclear cells. Additionally, FB49 arrests the cell cycle at the G1 phase and induces apoptosis and autophagy in treated medulloblastoma HD-MB03 cells [1].
Molecular Formula
C17H18N2O6S
Molecular Weight
378.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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