HDAC/JAK/BRD4-IN-1
Product Specifications
CAS Number
2755325-84-7
Target
JAK|||Apoptosis|||Epigenetic Reader Domain|||HDAC
Related Pathways
Chromatin/Epigenetic|||JAK/STAT signaling|||Apoptosis|||Tyrosine Kinase/Adaptors|||Angiogenesis|||Stem Cells|||DNA Damage/DNA Repair
Bioactivity
HDAC/JAK/BRD4-IN-1 (compound 25ap) is a potent triple inhibitor targeting HDAC, JAK, and BRD4. This compound not only inhibits cell proliferation but also induces apoptosis in MDA-MB-231 cells and demonstrates in vivo anticancer efficacy [1].
Smiles
N(C1=NC(NC2=CC=C(OCCN3CCCC3)C=C2)=NC=C1C)C4=CC=C(C(NO)=O)C=C4
Molecular Formula
C24H28N6O3
Molecular Weight
448.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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