HDAC/JAK/BRD4-IN-1

Product Specifications

CAS Number

2755325-84-7

Target

JAK|||Apoptosis|||Epigenetic Reader Domain|||HDAC

Related Pathways

Chromatin/Epigenetic|||JAK/STAT signaling|||Apoptosis|||Tyrosine Kinase/Adaptors|||Angiogenesis|||Stem Cells|||DNA Damage/DNA Repair

Bioactivity

HDAC/JAK/BRD4-IN-1 (compound 25ap) is a potent triple inhibitor targeting HDAC, JAK, and BRD4. This compound not only inhibits cell proliferation but also induces apoptosis in MDA-MB-231 cells and demonstrates in vivo anticancer efficacy [1].

Smiles

N(C1=NC(NC2=CC=C(OCCN3CCCC3)C=C2)=NC=C1C)C4=CC=C(C(NO)=O)C=C4

Molecular Formula

C24H28N6O3

Molecular Weight

448.52

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MF-0049999-01 5 mg

Cdk2/Cyclin Inhibitory Peptide I

Ask

View Details

MF-0049999-02 10 mg

Cdk2/Cyclin Inhibitory Peptide I

Ask

View Details

MF-0049999-03 25 mg

Cdk2/Cyclin Inhibitory Peptide I

Ask

View Details

NBP3-14081AF488 0.1 mL

Mouse Monoclonal ZNF81 Antibody (PCRP-ZNF81-2C7) [Alexa Fluor 488]

Ask

View Details

GC3769-500mg 500 mg

3,6-Di-O-acetyl-2-azido-2-deoxy-α-D-glucopyranose

Ask

View Details

RR202990L3 10 µg

Lgsn (NM_181383) Rat Tagged Lenti ORF Clone

Ask

View Details