PF-07202954
Product Specifications
CAS Number
2639372-47-5
Target
Acyltransferase
Related Pathways
Metabolism
Bioactivity
PF-07202954, a weakly basic diacylglycerol O-acyltransferase 2 (DGAT2) inhibitor, exhibits an inhibition concentration half-maximum (IC50) of 10 nM against human DGAT2 and effectively reduces liver triglyceride content in a rat model fed on a Western diet [1].
Smiles
O(C1=CC(C=2N=CC(C(N[C@H]3C[C@H](F)CNC3)=O)=CN2)=CN=C1)C4=C(OCC)C=CC=N4
Molecular Formula
C22H23FN6O3
Molecular Weight
438.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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