BQZ-485
Product Specifications
CAS Number
1906915-49-8
Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
BQZ-485, a potent GDI2 inhibitor, interacts with Tyr245 to disrupt the native GDI2-Rab1A interaction. This disruption impedes vesicular transport from the endoplasmic reticulum (ER) to the Golgi apparatus, triggering subsequent paraptosis events [1].
Smiles
O(CC1=CC(C)=CC(C)=C1)C=2C=C3[C@@]4(N(CCC3=CC2OCC5=CC(C)=CC(C)=C5)[C@@H](C)C[C@H](O)C4)[H]
Molecular Formula
C32H39NO3
Molecular Weight
485.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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