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BQZ-485

Product Specifications

CAS Number

1906915-49-8

Target

Apoptosis

Related Pathways

Apoptosis

Bioactivity

BQZ-485, a potent GDI2 inhibitor, interacts with Tyr245 to disrupt the native GDI2-Rab1A interaction. This disruption impedes vesicular transport from the endoplasmic reticulum (ER) to the Golgi apparatus, triggering subsequent paraptosis events [1].

Smiles

O(CC1=CC(C)=CC(C)=C1)C=2C=C3[C@@]4(N(CCC3=CC2OCC5=CC(C)=CC(C)=C5)[C@@H](C)C[C@H](O)C4)[H]

Molecular Formula

C32H39NO3

Molecular Weight

485.66

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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