TLR7 agonist 14

Product Specifications

CAS Number

2832199-45-6

Target

Others|||TLR

Related Pathways

Others|||Immunology/Inflammation

Bioactivity

Compound 17b, a TLR7 agonist also known as TLR7 agonist 14, exhibits high potency with an EC50 of 18 nM. It effectively activates mouse macrophages and human peripheral blood mononuclear cells (hPBMCs) at low-nanomolar concentrations [1].

Smiles

C(N1C=2C=3C(N=C(N)C2N=C1CCCC)=CC=CC3)C4=CC=C(NC(CCNC(OC(C)(C)C)=O)=O)C=C4

Molecular Formula

C29H36N6O3

Molecular Weight

516.63

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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