LRRK2-IN-10
Product Specifications
CAS Number
2704562-80-9
Target
LRRK2
Related Pathways
Autophagy
Bioactivity
LRRK2-IN-10 (compound 34) is a potent, mutation-selective, brain-penetrant inhibitor targeting G2019S-LRRK2 kinase with IC50 values of 11 nM for G2019S-LRRK2 pS935 and 5.2 nM for G2019S-LRRK2 pS1292, holding promise for research into Parkinson's disease [1].
Smiles
N(C=1C=C2C(=NNC2=CC1)C=3C=NOC3)[C@@H]4C=5C(CC4)=CC(C#N)=CC5
Molecular Formula
C20H15N5O
Molecular Weight
341.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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