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Caspase-3 activator 1

Product Specifications

Target

Pyroptosis

Related Pathways

Apoptosis, Immunology/Inflammation

Bioactivity

Caspase-3 activator 1 (compound 4b), a Ru (III) metal complex, effectively inhibits gastric tumor growth and metastasis by mediating caspase-3 cleavage, enabling Caspase-3 to process gasdermin E (GSDME), resulting in GSDME-N terminus production and perforation of the gastric tumor cell membrane. Furthermore, compound 4b induces pyroptosis and subsequent immune responses and can be incorporated with decitabine (DCT) into the 4b-DCT-Lip lipid delivery system [1].

Molecular Formula

C28H27N6O2RuS2

Molecular Weight

644.75

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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