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DHFR-IN-8

Product Specifications

Target

Others, DHFR, Antibacterial

Related Pathways

Metabolism, Microbiology/Virology, Cell Cycle/Checkpoint, Others, DNA Damage/DNA Repair

Bioactivity

DHFR-IN-8 (compound 6r), a dihydrofolate reductase (DHFR) inhibitor, disrupts purine and thymidylate biosynthesis critical for cell proliferation and growth. This compound effectively suppresses methicillin-resistant Staphylococcus aureus (MRSA) ATCC 43300 with an IC50 of 15.6 ng/mL in mouse models of systemic and thigh infections [1].

Molecular Formula

C18H14N6S

Molecular Weight

346.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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