DHFR-IN-8
Product Specifications
Target
Others|||DHFR|||Antibacterial
Related Pathways
Metabolism|||Microbiology/Virology|||Cell Cycle/Checkpoint|||Others|||DNA Damage/DNA Repair
Bioactivity
DHFR-IN-8 (compound 6r), a dihydrofolate reductase (DHFR) inhibitor, disrupts purine and thymidylate biosynthesis critical for cell proliferation and growth. This compound effectively suppresses methicillin-resistant Staphylococcus aureus (MRSA) ATCC 43300 with an IC50 of 15.6 ng/mL in mouse models of systemic and thigh infections [1].
Molecular Formula
C18H14N6S
Molecular Weight
346.41
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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