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CD38 inhibitor 3

Product Specifications

CAS Number

2857868-82-5

Target

CD38

Related Pathways

Immunology/Inflammation

Bioactivity

CD38 Inhibitor 3 (compound 1), with an IC50 of 11 nM, is a potent agent that enhances mitochondrial biogenesis, diminishes lactate levels, and augments both NAD+ content and Nrf2 expression. In a Pus1 -/- mouse model of mitochondrial myopathy, it also elevates muscle function and bolstering exercise capacity [1].

Smiles

C(NC=1C=NC(OCCOC)=NC1)(=O)C2=NC(=NC(C(F)(F)F)=C2)N3C=CN=C3

Molecular Formula

C16H14F3N7O3

Molecular Weight

409.32

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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