CD38 inhibitor 3
Product Specifications
CAS Number
2857868-82-5
Target
CD38
Related Pathways
Immunology/Inflammation
Bioactivity
CD38 Inhibitor 3 (compound 1), with an IC50 of 11 nM, is a potent agent that enhances mitochondrial biogenesis, diminishes lactate levels, and augments both NAD+ content and Nrf2 expression. In a Pus1 -/- mouse model of mitochondrial myopathy, it also elevates muscle function and bolstering exercise capacity [1].
Smiles
C(NC=1C=NC(OCCOC)=NC1)(=O)C2=NC(=NC(C(F)(F)F)=C2)N3C=CN=C3
Molecular Formula
C16H14F3N7O3
Molecular Weight
409.32
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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