EGFR/CDK2-IN-3
Product Specifications
Target
CDK, EGFR
Related Pathways
JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint
Bioactivity
EGFR/CDK2-IN-3 (compound 4b) is a dual inhibitor of EGFR and CDK-2 with IC50 values of 71.7 nM and 113.7 nM, respectively. It induces apoptosis in MCF-7 cells, arrests the cell cycle in the S phase, and exhibits significant anti-cancer cell toxicity, inhibiting MCF-7 cells with an IC50 of 3.16 μM [1].
Molecular Formula
C30H20N6OS
Molecular Weight
512.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC470954-100 1x 100 µL
Mucin 1 / EMA / Episialin / CD227 (HMPV), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
