RET-IN-25
Product Specifications
CAS Number
2965703-02-8
Target
C-RET|||Others
Related Pathways
Apoptosis|||Tyrosine Kinase/Adaptors|||Others
Bioactivity
RET-IN-25 (compound 6b) is an anticancer RET kinase inhibitor effective against medullary thyroid carcinoma (MTC), with half-maximal inhibitory concentrations (IC50s) of 3.6 ?M at 3 days and 3.0 ?M at 6 days in TT (C634R) MTC [1].
Smiles
O=[N+](C1=CC=C(N=C2)C(C3=C2C(NC(C4=CC=C(C=C4)C)=O)=C(C(OCC)=O)S3)=C1)[O-]
Molecular Formula
C22H17N3O5S
Molecular Weight
435.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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