RET-IN-25

Product Specifications

CAS Number

2965703-02-8

Target

C-RET|||Others

Related Pathways

Apoptosis|||Tyrosine Kinase/Adaptors|||Others

Bioactivity

RET-IN-25 (compound 6b) is an anticancer RET kinase inhibitor effective against medullary thyroid carcinoma (MTC), with half-maximal inhibitory concentrations (IC50s) of 3.6 ?M at 3 days and 3.0 ?M at 6 days in TT (C634R) MTC [1].

Smiles

O=[N+](C1=CC=C(N=C2)C(C3=C2C(NC(C4=CC=C(C=C4)C)=O)=C(C(OCC)=O)S3)=C1)[O-]

Molecular Formula

C22H17N3O5S

Molecular Weight

435.45

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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