PDK-IN-2
Product Specifications
Target
Dehydrogenase|||Others|||Mitochondrial Metabolism
Related Pathways
Metabolism|||Others
Bioactivity
PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells. It promotes mitochondrial bioenergetics, reduces glycolytic activity, and triggers apoptosis via the mitochondrial pathway. Additionally, PDK-IN-2 has been shown to impede tumor growth in a 4T1 syngeneic mouse model [1].
Molecular Formula
C17H23AsCl2N2O2S2
Molecular Weight
497.33
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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