What is the catalog number for PDK-IN-2?

The catalog number for PDK-IN-2 is T79723.

What sizes are available for PDK-IN-2?

PDK-IN-2 is available in the following size(s): 5 mg, 50 mg.

How many pack sizes does PDK-IN-2 come in?

PDK-IN-2 is available in 2 different pack sizes.

Is PDK-IN-2 in stock?

PDK-IN-2 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PDK-IN-2?

PDK-IN-2 is manufactured by Molfinity.

What is the estimated delivery time for PDK-IN-2?

Estimated delivery time for PDK-IN-2 is approximately 10 business day(s), depending on your location.

PDK-IN-2

Product Specifications

Target

Dehydrogenase, Others, Mitochondrial Metabolism

Related Pathways

Metabolism, Others

Bioactivity

PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells. It promotes mitochondrial bioenergetics, reduces glycolytic activity, and triggers apoptosis via the mitochondrial pathway. Additionally, PDK-IN-2 has been shown to impede tumor growth in a 4T1 syngeneic mouse model [1].