SSE1806
Product Specifications
Target
Apoptosis, Others, Microtubule Associated
Related Pathways
Apoptosis, Others, Cytoskeletal Signaling
Bioactivity
SSE1806, a podophyllotoxin derivative (a natural antimitotic agent), functions as a microtubule/tubulin inhibitor, exhibiting potent anticancer and antiproliferative properties. It demonstrates a GI50 for inhibiting cancer cell growth between 1.29-21.15 μM. This compound induces mitotic disruption and G2/M phase arrest, upregulates p53 expression, and suppresses the growth of colon cancer organoids. Notably, SSE1806 can counteract multidrug resistance in cell lines that overexpress MDR-1 [1].
Molecular Formula
C21H18N2O5
Molecular Weight
378.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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